Endocrine Abstracts

The National Paediatric Diabetes Audit (NPDA) has now been established for 9 years and collects data on standards of care as defined by the National Institute for Clinical Excellence (NICE). These include demographics of paediatric diabetes, care process completion rates and outcomes.Since April 2011 the NPDA has been managed by the Royal College of Paediatrics and Child Health (RCPCH) which comprises a project board advised by specific working groups as...

A well-term baby born to consanguineous healthy Yemenese parents was observed in the hospital as parents had lost previous three babies (both male and female) within 10 days of age (in Yemen). These babies who were initially well were reported to have developed a rash and then collapsed and died. Post-mortems were not done. This baby who appeared well at birth, also developed a facial rash on day seven and was found to have hyponatremia and severe hyperkalemia, albeit a normal...

Introduction: The presence of thyroid peroxidase (TPO) antibodies in euthyroid children poses a potential risk for the development of autoimmune hypothyroidism. Little is known about the ontogeny of this process. This retrospective study aims to estimate the risk of developing hypothyroidism in euthyroid children with raised TPO antibodies and provide a guideline for follow up.Methods: Children 0–16 years with raised TPO antibodies (1996–2005) ...

Background: The safety of GH replacement in patients with craniopharyngioma has not been clearly elucidated.Aim: To assess whether GH replacement increases the risk of craniopharyngioma recurrence.Patients and Methods: The records of the patients with craniopharyngioma followed-up at the Departments of Endocrinology and Paediatrics between 1/1964-6/2004 were reviewed. The recurrence risks of GH-treated and non-GH-treated patients w...